28.  Ewing's sarcoma

Answer:
Ewing’s sarcoma is one of the common primary childhood sarcomas of bone but only rarely arises in the bones of the hand. This tumor most commonly occurs in the first or second decade of life. The tumor most commonly arises in the metacarpals or phalanges with extensive soft tissue involvement. Radiographs typically reveal a large lytic, destructive, expansile lesion with associated soft tissue involvement. Histologically sheets of uniform small round “blue” cells with centrally placed nuclei and scant, faintly staining cytoplasm are found. Treatment involves ablative surgery in the setting of systemic treatment with chemotherapy. Local control with external beam radiation has been reported.
 

 NEXT QUESTION