Melanoma

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1.  Compare labelled and Clark’s levels.  Which is better to use?

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2.  What skin margins do you excise for a:  1-mm melanoma,  2-mm melanoma,  3-mm melanoma,  Hutchinson freckle,  in-situ melanoma?  How did the 5-cm rule originate?

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3.  What are the most significant prognostic indicators to affect the outcome of melanoma?  Are BANS, acrolentiginous, and pregnant patients really worse off?

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4.  What is the five- and ten-year survival of the various stages of melanoma?

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5.  When you do a wide excision, must fascia be removed?  What is Sappey's line?

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6.  Should you do an elective lymph node dissection for a: 1-mm melanoma, 3-mm melanoma, 5-mm melanoma?

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7.  You biopsy a lymph node and it is melanoma.  You cannot find the primary - what do you do?  What is the outcome of these patients?

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8.  Does regional perfusion work for melanoma?  How about chemotherapy and RT?  Discuss interferon.  (PRS 1997; 99:1023)

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9.  Your patient has a single palpable lymph node in the groin after wide resection of a melanoma in the past.  Metastatic workup is negative.  Should you do a superficial or deep node dissection?  (PRS 1991; 88:810  Archives of Surgery 1989; 124:162)

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10.  Your post-op melanoma patient has a single lung met on CT.  What should you do?  What about a single liver met?  Or what if there were palpable nodes in their axilla and supraclavicular areas with a negative metastatic workup?

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11.  Does an incisional biopsy spread melanoma cells?

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12.  Do gallium scans and labeled monoclonal antibody scans work better than CT's for metastatic work-up?

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13.  How is a sentinel node done?  Is it really representative of the entire nodal basin?  How is the pathology done on a sentinel node?

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14.  A five-year-old child comes to you who has a 12 x 12-cm hairy nevus.  What are the chances that he will get melanoma?  What if the child’s hairy nevus is 4 x 6 cm?  When and how should these nevi be removed?

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15.  What is dysplastic nevus syndrome?  What is the BK mole syndrome?  Is melanoma familial?

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