Wound Healing

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1. Tell us about the role of the macrophage and lymphocyte in wound healing.

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2. Tell us about fibronectin, ground substance and collagen.  How long does collagen increase?  When is the wound strong?  Does it ever attain the full strength of unwounded skin?

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3. What does infection do to the wound healing process?

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4. What do steroids do to wound healing?  How do you treat these patients?

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5.  How does diabetes affect wound healing?

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6.  How does smoking affect wound healing?

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7.  How does chemotherapy affect wound healing?

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8.  Your patient asks you, "Doctor, can I use vitamin E, zinc, aloe vera, or cocoa butter on my scar?"  What do you say?

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9.  Review epithelial and platelet derived factors.  Read Clinics in Plastic Surgery 1990, p.421; PRS 1991, 88:189; Annals of PS 1992, 29:123.

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10.  Mothers all over America tell kids not to get their sutures wet.  Can they be wrong?  (Amer Journal of Surgery 1981, vol. 141:358;  PRS 1988, vol.81:82)

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11.  What does anemia do to wound healing?

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12.  Tell us about the role of the myofibroblast and how contraction takes place.

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13.  What is the best solution for a wet to dry dressing?  (PRS 75:394, 1985 & Annals of PS 27: 265, 1991)

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14.  Does silicone gel sheeting decrease scarring?

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15.   Does electrical stimulation help wounds heal?  (PRS 89:891, 1992; Annals of PS 29: 328, 1992)

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16.   How is a keloid different biochemically and histologically from a normal scar?

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17.  Tell us about the successful treatments for keloids. Read PRS 84:829, 1989.

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18.  How are oxygen free radicals generated and what is their role in wound healing?

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19.  Does a paraplegic heal as well as a non-paraplegic?  Read PRS 98:1063, 1996.

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20.  What suture is best to get the prettiest wound?  Read PRS 98:817, 1996.

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21.  How is fetal wound healing different from yours?

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22.  What role does zinc play in wound healing?

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23.  Do you advocate vacuum-assisted closure? (Annals 1997; 38:553 & 563)

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24.  What does Toradol do to wound healing? (Annals of Plastic Surgery 37:147, 1996)

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25.  Discuss the 5 types of collagen.

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26.  Discuss the classic principles of wound closure by Halsted.

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