Answer:
In their article, “Cellular and Bacterial Toxicities of Topical Antimicrobials,” Lineaweaver, McMorris, and Soucy report that acetic acid and hydrogen peroxide are toxic to fibroblasts at various concentrations, and their use should be avoided. However, povidone-iodine (0.001%) and sodium hypochlorite (0.005%) are bactericidal while not damaging to fibroblasts, although there is no proof at this time that they are in any way beneficial to wound healing. In Annals 27:265, 1991, McKenna's article, “Antiseptic Effectiveness with Fibroblast Preservation,” showed that sodium-hypochlorite (0.005%) can be used as a debriding and topical antibacterial agent for wounds and skin ulcers without inhibiting fibroblast activity essential to normal wound repair.